DOTA及其衍生物是应用广泛的新型双功能螯合剂之一.DOTA及其衍生物不仅具有成熟的合成工艺路线,还具有良好的配位和螯合能力,DOTA-多肽分子探针作为MRI对比剂,核素靶向显像剂和放射性药物在生物医学领域被广泛应用.DOTA及其衍生物可以被用来标记修饰以下配合物：
DOTA功能螯合剂标记多肽；p-NO2-Bn-DOTA；DOTA修饰多肽螯合金属配合物；p-NH2-Bn-DOTA；111In-DOTA-PEG4-cRGDfk；p-NH2-Bn-DOTA-tetra(t-Bu-ester)；111In-DOTA-Lysine-cRGDfk；DOTA-tris (t-Bu ester)；DOTA螯合镧系金属离子定制；DOTA-mono-NHS-tris(t-Bu ester)等。
我们有自己的独立有机合成实验室，可以自主生产合成各种大环类配体及螯合剂，我们可以合成大环配体、双功能螯合剂、环糊精、聚醚、葫芦脲、卟啉、酞菁、磁共振试剂、反应中间体等。
相关列表
CY3/CY5/CY7/CY7.5/ICG-DOTA
CY3/CY5/CY7/CY7.5/ICG-NOTA
DOTA-(Tyr3)-Octreotate
DOTA-111In-CY7
158Gd-ESMA
DOTA-E-c(RGDf K)
Gd-DOTA-4AmP
Gd-DOTP
Gd-DOTA-YHWYGYTPQNVI
Gd-DOTA-HYPYAHPTHPSW
DOTA功能螯合剂标记多肽
DOTA修饰多肽螯合金属配合物
111In-DOTA-PEG4-cRGDfk
111In-DOTA-Lysine-cRGDfk
DOTA螯合镧系金属离子定制
Gd-DOTA-ACL
Ga-DOTA-多肽
DOTA-RGD
金属离子独立地选自Cu，Fe，In，Tm，Yb，Y，Gd，Eu和镧系元素
dendrimer-Gd-DOTA
Gd-DOTA-PLGA
Gd-EDTA
DTPA-Gd
Gd-DOTA-多肽
Gd-DOTA-蛋白
Gd-DOTA-多糖
Ga-DOTA-Tyr3-octreotide
Ga-DOTA-cRGD
Ga-DOTA-NOC
4-Aminobutyl-DOTA CAS:753421-63-5
p-NH?-Bn-DTPA CAS:102650-29-3
p-NH?-Bn-DTPA-penta (t-Bu ester) CAS:205956-41-0
p-SCN-Bn-DTPA CAS:102650-30-6
p-NH?-Bn-CHX-A-DTPA CAS:1105741-38-5
p-SCN-Bn-CHX-A-DTPA CAS:157380-45-5
DTPA-tetra (t-Bu ester) CAS:174267-71-1
Maleimido-mono-amide-DTPA CAS:2032239-75-9
p-NH?-Bn-PCTA CAS:2125661-64-3
p-SCN-Bn-PCTA CAS:949147-44-8
p-NH?-Bn-oxo-DO3A CAS:2125661-90-5
p-SCN-Bn-oxo-DO3A CAS:1370442-99-1
p-NH2-Bn-NOTA CAS:142131-37-1
p-SCN-Bn-NOTA CAS:147597-66-8
NO2A-Butyne-bis (t-Butyl ester) CAS:2125661-91-6
NOTA-bis(t-Bu ester) CAS:1161415-28-6
Maleimido-mono-amide-NOTA CAS:
NO2A-Butyne CAS:2089035-56-1
NO2A-Azide CAS:2125661-92-7
NODAGA-tris(t-Bu ester) CAS:438553-50-3
p-SCN-Bn-Deferoxamine CAS:1222468-90-7
Deferoxamine-maleimide CAS:1638156-31-6
Deferoxamine-DBCO
DOTA-Biotin-Sarcosine CAS:180978-54-5
DO3A-Serotonin CAS:2125661-93-8
DOTATATE CAS:177943-89-4
DOTA CAS:60239-18-1
DOTMA CAS:148408-89-3
DOTAM CAS:157599-02-5
CB-Cyclam CAS:130701-19-8
CB-TE2A CAS:313229-90-2
DOTA-4AMP CAS:254444-71-8
NOTA CAS:56491-86-2
NOTP CAS:83834-39-3
Tm-DOTA CAS:78063-83-9
Gd-DOTA CAS:72573-82-1
Tm-DOTP CAS:30859-88-
Tm-DOTMA CAS:2126179-30-2
Eu-DOTA-4Am CAS:481668-57-9
zzj 2021.3.23