名 称:DBCO-PEG4-Desthiobiotin
Desthiobiotin-PEG4-DBCO
CAS号: 2032788-37-5
外 观:无色至微黄色的油
分子式:C39H51N5O8
分子量:719.87
纯度:>95%
溶解度:Water, DMSO, DMF
保存条件:-20℃ 12个月
产品描述:DBCO-PEG4-Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.
结构式:
其他点击试剂:
氮杂二苯并环辛炔胺
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分子式:C28H26N4O8S
以上信息均由陕西新研博美生物科技有限公司提供技术支持