本来是个用WPF的C#程序，一直Crash。后面做实验，新建C++工程，建32位，64位工程对比来看，发现不是因为WFP的原因，定位是64位程序的原因。
于用于SafeMode，看Log，显示是msvsmon.exe加载出错，查到微软说明文档：
Debug a 64-bit Application
To try debugging a 64-bit application:
Create a Visual Studio solution, for example a C# console application.
Set the configuration to 64-bit using the Configuration Manager. For more information, see How to: Configure Projects to Target Platforms.
At this point the 64-bit version of the remote debugger (msvsmon.exe) starts. It runs as long as the solution with the 64-bit configuration is open.
Start debugging. You should have the same experience as with a 32-bit configuration. If you get errors, see the Troubleshooting section below.
64位需要启动msvsmon.exe来进行调试，又查了很多资料，官方也说有可能是防火墙禁了这个服务，关了也没有用。但想想，总是和网络有关系的，想了想自己的网络设置和同事有什么不一样。。。。原来是我用了Astrill，stackoverflow上也有人遇到相同的问题，Astrill会把本地IP给改了，卸载了就可以正常启动调试程序了。