服务端代码：

import hashlib
import time
KEY = 'RTYUIFGHJKVBNM'


def gen_key(ctime):
    md5 = hashlib.md5()
    key = "{}|{}".format(KEY,ctime)
    md5.update(key.encode('utf-8'))
    return md5.hexdigest()


class TestView(APIView):
    def post(self,request):
        print(request.data)
        # print(request._request.GET.get('KEY'))
        key = request.query_params.get('key')
        ctime = request.query_params.get('time')
        now = time.time()
        if now - float(ctime) > 3:
            return Response('校验失败，Key超时')

        if key != gen_key(ctime):
            return  Response('校验失败')

        return Response('ok')

客户端代码：

import requests
import time
import hashlib

KEY = 'RTYUIFGHJKVBNM'
data = {'k1':'v1'}

def gen_key(ctime):
    md5 = hashlib.md5()
    key = "{}|{}".format(KEY,ctime)
    md5.update(key.encode('utf-8'))
    return md5.hexdigest()

ctime = time.time()
key = gen_key(ctime)
time.sleep(3)
ret = requests.post(
    url='http://127.0.0.1:8000/app01/test/',
    data = data,
    params = {'key':key,'time':ctime}
)
print(ret.text)